Dexmedetomidine: A Novel Sedative-Analgesic Agent
نویسندگان
چکیده
منابع مشابه
Dexmedetomidine: a novel sedative-analgesic agent.
Since the first report of clonidine, an alpha2-adrenoceptor agonist, the indications for this class of drugs have continued to expand. In December 1999, dexmedetomidine was approved as the most recent agent in this group and was introduced into clinical practice as a short-term sedative (<24 hours). Alpha2-adrenoceptor agonists have several beneficial actions during the perioperative period. Th...
متن کاملDexmedetomidine hydrochloride as a long-term sedative
Dexmedetomidine undoubtedly is a useful sedative in the intensive care setting because it has a minimal effect on the respiratory system. Dexmedetomidine infusions lasting more than 24 hours have not been approved since the first approval was acquired in the US in 1999. However, in 2008, dexmedetomidine infusions for prolonged use were approved in Colombia and in the Dominican Republic, and the...
متن کاملAnalgesic and sedative effects of intranasal dexmedetomidine in third molar surgery under local anaesthesia.
BACKGROUND Dexmedetomidine (DEX) is an alpha 2-adrenoreceptor agonist, which induces sedation and analgesia. This study aimed to determine whether intranasal DEX offered perioperative sedation and better postoperative analgesia. METHODS Patients having unilateral third molar surgery under local anaesthesia were recruited and allocated to receive either intranasal DEX 1 µg kg(-1) (Group D) or ...
متن کاملDexmedetomidine as a Sedative Agent in Critically Ill Patients: A Meta-Analysis of Randomized Controlled Trials
INTRODUCTION The effect of dexmedetomidine on length of intensive care unit (ICU) stay and time to extubation is still unclear. MATERIALS AND METHODS Pertinent studies were independently searched in BioMedCentral, PubMed, Embase, and the Cochrane Central Register of clinical trials (updated February first 2013). Randomized studies (dexmedetomidine versus any comparator) were included if inclu...
متن کاملDexmedetomidine as a primary sedative agent after single-stage airway reconstruction.
OBJECTIVE To examine the outcomes of children receiving dexmedetomidine after single-stage airway reconstruction. STUDY DESIGN Historical cohort study. SETTING Tertiary care children's hospital. SUBJECTS AND METHODS Of 61 eligible patients, 50 children undergoing single-stage airway reconstruction were included in the study. Thirty children received dexmedetomidine (Dex) as a primary seda...
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ژورنال
عنوان ژورنال: Baylor University Medical Center Proceedings
سال: 2001
ISSN: 0899-8280,1525-3252
DOI: 10.1080/08998280.2001.11927725